Assay Detail
ADMET
CHEMBL954838
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Cytotoxicity against human normal fibroblast after 1 day by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | Fibroblast |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.50 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL986 | RETINOL | 4.0 | 1 | 4.60 |
| CHEMBL451039 | RETINYLRETINOATE | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL986 | RETINOL | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL451039 | RETINYLRETINOATE | IC50 | = | 40000.0 | nM | 4.40 |