Assay Detail
Binding
CHEMBL955916
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Inhibition of Aurora B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: potent inhibitors of the IGF-1R receptor tyrosine kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.05 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL476451 | — | — | 1 | 8.30 |
| CHEMBL1964272 | — | — | 1 | 5.80 |
| CHEMBL514868 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL476451 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL1964272 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL514868 | — | IC50 | > | 10000.0 | nM | - |