Assay Detail
Functional
CHEMBL956445
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 assessed as syncytium inhibition by cell-cell fusion assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
A novel fluorescence intensity screening assay identifies new low-molecular-weight inhibitors of the gp41 coiled-coil domain of human immunodeficiency virus type 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.87 | 5.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL264938 | GALLOCATECHIN GALLATE | — | 1 | 5.37 |
| CHEMBL504538 | — | — | 1 | 4.36 |
| CHEMBL525426 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL264938 | GALLOCATECHIN GALLATE | IC50 | = | 4320.0 | nM | 5.37 |
| CHEMBL504538 | — | IC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL525426 | — | IC50 | - | — | - |