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Assay Detail

CHEMBL956561

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]CP-55940 from CB1 receptor in mouse brain at 100 nM
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Tissue Brain
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 1 (CHEMBL3037)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels.
Nomura DK, Hudak CS, Ward AM, Burston JJ, Issa RS, Fisher KJ, Abood ME, Wiley JL, Lichtman AH, Casida JE.
Bioorg Med Chem Lett (2008) 18 : 5875 -5878
PubMed 18752948 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.07 9.07
Bmax 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL444970 CHLORPHRIFOS OXON 2 9.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL444970 CHLORPHRIFOS OXON Kd = 0.86 nM 9.07
CHEMBL444970 CHLORPHRIFOS OXON Bmax = 0.17 pmol/mg -