Assay Detail
Functional
CHEMBL956563
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at CB1 receptor in mouse brain membrane assessed as stimulation of GTPgammaS binding
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.30 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL333149 | ISOPROPYL DODECYLFLUOROPHOSPHONATE | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL333149 | ISOPROPYL DODECYLFLUOROPHOSPHONATE | EC50 | = | 500.0 | nM | 6.30 |