Assay Detail
Functional
CHEMBL957712
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplatelet activity against rabbit platelet assessed as inhibition of platelet-activating factor-induced platelet aggregation at 20 uM preincubated 3 mins before PAF challenge by turbidimetric method relative to control
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Cell Type | Platelet |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive constituents of Morus australis and Broussonetia papyrifera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.60 | 6.00 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL516319 | BROUSSOFLAVONOL E | — | 1 | 6.00 |
| CHEMBL463019 | BROUSSOAURONE A | — | 1 | 5.92 |
| CHEMBL466162 | BROUSSOFLAVAN A | — | 1 | 5.68 |
| CHEMBL464007 | BROUSSOFLAVONOL F | — | 1 | 5.57 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | 2.0 | 1 | 4.84 |
| CHEMBL464006 | MORUSIN | — | 1 | - |
| CHEMBL518543 | KUWANON C | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL516319 | BROUSSOFLAVONOL E | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL463019 | BROUSSOAURONE A | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL466162 | BROUSSOFLAVAN A | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL464007 | BROUSSOFLAVONOL F | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | IC50 | = | 14500.0 | nM | 4.84 |
| CHEMBL464006 | MORUSIN | Activity | = | 81.3 | % | - |
| CHEMBL518543 | KUWANON C | Activity | = | 78.8 | % | - |