Assay Detail
Binding
CHEMBL958727
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity against estrogen receptor alpha
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Recent developments in fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.45 | 7.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL81 | RALOXIFENE | 4.0 | 1 | 7.66 |
| CHEMBL431698 | RALOXIFENE CORE | — | 2 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL81 | RALOXIFENE | EC50 | = | 22.0 | nM | 7.66 |
| CHEMBL431698 | RALOXIFENE CORE | EC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL431698 | RALOXIFENE CORE | EC50 | = | 1400.0 | nM | 5.85 |