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Assay Detail

CHEMBL958842

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV1 in ATH8 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Cell Type ATH-8
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Pharmacokinetics of the anti-human immunodeficiency virus agent 1-(beta-D-dioxolane)thymine in rhesus monkeys.
Asif G, Hurwitz SJ, Obikhod A, Delinsky D, Narayanasamy J, Chu CK, McClure HM, Schinazi RF.
Antimicrob Agents Chemother (2007) 51 : 2424 -2429
PubMed 17485498 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.70 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL297319 1 4.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL297319 EC50 = 20000.0 nM 4.70