Assay Detail
Functional
CHEMBL959043
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mouse PPARdelta receptor by cell based transient transfection assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor delta (CHEMBL2458) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
The discovery of equipotent PPARalpha/gamma dual activators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.15 | 5.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL455157 | — | — | 1 | 5.15 |
| CHEMBL518348 | — | — | 1 | - |
| CHEMBL460278 | — | — | 1 | - |
| CHEMBL516964 | — | — | 1 | - |
| CHEMBL472399 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL455157 | — | EC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL518348 | — | EC50 | > | 25000.0 | nM | - |
| CHEMBL460278 | — | EC50 | > | 25000.0 | nM | - |
| CHEMBL516964 | — | EC50 | > | 25000.0 | nM | - |
| CHEMBL472399 | — | EC50 | > | 25000.0 | nM | - |