Assay Detail
Functional
CHEMBL959044
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mouse PPARgamma receptor by cell based transient transfection assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL2459) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
The discovery of equipotent PPARalpha/gamma dual activators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.45 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL518348 | — | — | 1 | 7.96 |
| CHEMBL455157 | — | — | 1 | 7.80 |
| CHEMBL460278 | — | — | 1 | 7.44 |
| CHEMBL472399 | — | — | 1 | 7.22 |
| CHEMBL516964 | — | — | 1 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL518348 | — | EC50 | = | 11.0 | nM | 7.96 |
| CHEMBL455157 | — | EC50 | = | 16.0 | nM | 7.80 |
| CHEMBL460278 | — | EC50 | = | 36.0 | nM | 7.44 |
| CHEMBL472399 | — | EC50 | = | 60.0 | nM | 7.22 |
| CHEMBL516964 | — | EC50 | = | 150.0 | nM | 6.82 |