Assay Detail
Binding
CHEMBL959583
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Inhibition of human recombinant cathepsin K by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Substrate optimization for monitoring cathepsin C activity in live cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.86 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL486232 | — | — | 1 | 8.92 |
| CHEMBL514348 | — | — | 1 | 6.92 |
| CHEMBL212521 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL486232 | — | Ki | = | 1.2 | nM | 8.92 |
| CHEMBL514348 | — | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL212521 | — | Ki | = | 18000.0 | nM | 4.75 |