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Assay Detail

CHEMBL960234

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Photosystem 2 in spinach thylakoid membrane assessed as inhibition of photosynthetic oxygen evolution
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Spinacia oleracea
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

PSII inhibitory activity of resorcinolic lipids from Sorghum bicolor.
Rimando AM, Dayan FE, Streibig JC.
J Nat Prod (2003) 66 : 42 -45
PubMed 12542343 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.86 7.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL463022 1 7.05
CHEMBL463021 SORGOLEONE 1 7.05
CHEMBL456854 E565 1 6.70
CHEMBL278489 DCMU 1 6.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL463022 IC50 = 90.0 nM 7.05
CHEMBL463021 SORGOLEONE IC50 = 90.0 nM 7.05
CHEMBL456854 E565 IC50 = 200.0 nM 6.70
CHEMBL278489 DCMU IC50 = 230.0 nM 6.64