Assay Detail
Binding
CHEMBL960396
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Inhibition of EGFR
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.86 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL78257 | TYRPHOSTIN 51 | — | 1 | 6.10 |
| CHEMBL77030 | TYRPHOSTIN 47 | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL78257 | TYRPHOSTIN 51 | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL77030 | TYRPHOSTIN 47 | IC50 | = | 2400.0 | nM | 5.62 |