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Assay Detail

CHEMBL960984

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CCR5
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

C-C chemokine receptor type 5 (CHEMBL274)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design, synthesis, and structure-activity relationship of novel CCR2 antagonists.
Kothandaraman S, Donnely KL, Butora G, Jiao R, Pasternak A, Morriello GJ, Goble SD, Zhou C, Mills SG, Maccoss M, Vicario PP, Ayala JM, Demartino JA, Struthers M, Cascieri MA, Yang L.
Bioorg Med Chem Lett (2009) 19 : 1830 -1834
PubMed 19237282 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.85 8.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL41275 1 8.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL41275 IC50 = 1.4 nM 8.85