Assay Detail
Binding
CHEMBL961029
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Binding affinity to 5HT2C receptor by competitive binding experiment
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.19 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL62919 | ALTANSERIN | 2.0 | 1 | 7.40 |
| CHEMBL74355 | VOLINANSERIN | 3.0 | 1 | 6.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL62919 | ALTANSERIN | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL74355 | VOLINANSERIN | Ki | = | 107.0 | nM | 6.97 |