Assay Detail
Functional
CHEMBL961860
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Antimalarial activity against Plasmodium falciparum W2 after 24 hrs by [3H]hypoxanthine uptake
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Efficacy of scopadulcic acid A against Plasmodium falciparum in vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.54 | 8.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL416956 | MEFLOQUINE | 4.0 | 1 | 8.32 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 6.58 |
| CHEMBL464656 | SCOPADULCIC ACID A | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL416956 | MEFLOQUINE | IC50 | = | 4.8 | nM | 8.32 |
| CHEMBL76 | CHLOROQUINE | IC50 | = | 266.0 | nM | 6.58 |
| CHEMBL464656 | SCOPADULCIC ACID A | IC50 | = | 19000.0 | nM | 4.72 |