Assay Detail
Functional
CHEMBL961871
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Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Constituents of Chinese propolis and their antiproliferative activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 16 | 4.99 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 7.40 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 5.44 |
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | — | 1 | 4.55 |
| CHEMBL133714 | BENZYL CAFFEATE | — | 1 | 4.46 |
| CHEMBL309490 | GALANGIN | — | 1 | 4.03 |
| CHEMBL457076 | BENZYL FERULATE | — | 1 | 4.03 |
| CHEMBL464454 | — | — | 1 | - |
| CHEMBL465658 | — | — | 1 | - |
| CHEMBL117 | CHRYSIN | — | 1 | - |
| CHEMBL464966 | IZALPININ | — | 1 | - |
| CHEMBL28 | APIGENIN | — | 1 | - |
| CHEMBL164841 | TECHTOCHRYSIN | — | 1 | - |
| CHEMBL254613 | PINOSTROBIN | — | 1 | - |
| CHEMBL399910 | PINOCEMBRIN | 2.0 | 1 | - |
| CHEMBL233295 | ISOFERULIC ACID | — | 1 | - |
| CHEMBL320295 | O,O'-DIMETHYLCAFFEIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL185 | FLUOROURACIL | EC50 | = | 3610.0 | nM | 5.44 |
| CHEMBL319244 | CAFFEIC ACID PHENETHYL ESTER | EC50 | = | 27900.0 | nM | 4.55 |
| CHEMBL133714 | BENZYL CAFFEATE | EC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL309490 | GALANGIN | EC50 | = | 93600.0 | nM | 4.03 |
| CHEMBL457076 | BENZYL FERULATE | EC50 | = | 92800.0 | nM | 4.03 |
| CHEMBL464454 | — | EC50 | = | 160000.0 | nM | - |
| CHEMBL465658 | — | EC50 | > | 270000.0 | nM | - |
| CHEMBL117 | CHRYSIN | EC50 | = | 233000.0 | nM | - |
| CHEMBL464966 | IZALPININ | EC50 | > | 350000.0 | nM | - |
| CHEMBL28 | APIGENIN | EC50 | = | 101000.0 | nM | - |
| CHEMBL164841 | TECHTOCHRYSIN | EC50 | > | 370000.0 | nM | - |
| CHEMBL254613 | PINOSTROBIN | EC50 | > | 370000.0 | nM | - |
| CHEMBL399910 | PINOCEMBRIN | EC50 | = | 229000.0 | nM | - |
| CHEMBL233295 | ISOFERULIC ACID | EC50 | > | 515000.0 | nM | - |
| CHEMBL320295 | O,O'-DIMETHYLCAFFEIC ACID | EC50 | > | 480000.0 | nM | - |