Assay Detail
Functional
CHEMBL962074
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Antioxidant activity assessed as inhibition of lactoperoxidase-catalyzed oxidation of 2,2'-azinobis(3-ethylbenzthione 6-sulfonic acid)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Interaction of methimazole with I2: X-ray crystal structure of the charge transfer complex methimazole-I2. implications for the mechanism of action of methimazole-based antithyroid drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.55 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL452810 | — | — | 1 | 5.85 |
| CHEMBL1515 | METHIMAZOLE | 4.0 | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL452810 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL1515 | METHIMAZOLE | IC50 | = | 5600.0 | nM | 5.25 |