Assay Detail
Functional
CHEMBL962387
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
4
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
4,4'-Dihydroxy-trans-stilbene, a resveratrol analogue, exhibited enhanced antioxidant activity and cytotoxicity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.04 | 5.48 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44657 | ETOPOSIDE | 4.0 | 1 | 5.48 |
| CHEMBL196731 | TRANS-4,4'-DIHYDROXYSTILBENE | — | 1 | 5.19 |
| CHEMBL165 | RESVERATROL | 3.0 | 2 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44657 | ETOPOSIDE | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL196731 | TRANS-4,4'-DIHYDROXYSTILBENE | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL165 | RESVERATROL | IC50 | = | 36300.0 | nM | 4.44 |
| CHEMBL165 | RESVERATROL | Activity | - | — | - |