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Assay Detail

CHEMBL962455

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Toxicity
Toxicity against PHA-activated human peripheral lymphocytes assessed as cell viability after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type Lymphocyte
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

(+/-)-3,4-Dihydroxy-8,9-methylenedioxypterocarpan and derivatives: cytotoxic effect on human leukemia cell lines.
Netto CD, Santos ES, Castro CP, da Silva AJ, Rumjanek VM, Costa PR.
Eur J Med Chem (2009) 44 : 920 -925
PubMed 18468732 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.62 5.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL476857 1 5.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL476857 IC50 = 2400.0 nM 5.62