Assay Detail
ADMET
CHEMBL963899
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Cytotoxicity against mouse 3T3L1 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | 3T3-L1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluation of biotin-labeled (-)-ternatin, a potent fat-accumulation inhibitor against 3T3-L1 adipocytes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.55 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL394301 | TERNATIN (PEPTIDE) | — | 1 | 6.55 |
| CHEMBL507949 | — | — | 1 | - |
| CHEMBL505545 | — | — | 1 | - |
| CHEMBL447542 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL394301 | TERNATIN (PEPTIDE) | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL507949 | — | IC50 | > | 86000.0 | nM | - |
| CHEMBL505545 | — | IC50 | > | 160000.0 | nM | - |
| CHEMBL447542 | — | IC50 | > | 5200.0 | nM | - |