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Assay Detail

CHEMBL964244

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FGFR1K autophosphorylation activity assessed as [32P] incorporation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Fibroblast growth factor receptor 1 (CHEMBL3650)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors.
Mohammadi M, McMahon G, Sun L, Tang C, Hirth P, Yeh BK, Hubbard SR, Schlessinger J.
Science (1997) 276 : 955 -960
PubMed 9139660 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL315546 1 5.00
CHEMBL89363 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL315546 IC50 = 10000.0 nM 5.00
CHEMBL89363 IC50 = 10000.0 nM 5.00