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Assay Detail

CHEMBL964449

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Growth inhibition of mouse MS1 cells by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Mus musculus
Cell Type MS1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis.
Zhao Y, Zhou Y, O'Boyle KM, Murphy PV.
Bioorg Med Chem (2008) 16 : 6333 -6337
PubMed 18504133 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL254117 1 5.70
CHEMBL254339 1 5.70
CHEMBL254145 1 5.70
CHEMBL401628 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL254117 IC50 = 2000.0 nM 5.70
CHEMBL254339 IC50 = 2000.0 nM 5.70
CHEMBL254145 IC50 = 2000.0 nM 5.70
CHEMBL401628 IC50 = 2000.0 nM 5.70