Assay Detail
Functional
CHEMBL964507
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Cytotoxicity against human U87 cells by side flank model relative to control
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-87MG ATCC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Exploring the substituent effects on a novel series of C1'-dimethyl-aryl Delta8-tetrahydrocannabinol analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.57 | 5.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL519575 | — | — | 1 | 5.74 |
| CHEMBL471297 | — | — | 1 | 5.60 |
| CHEMBL471123 | — | — | 1 | 5.59 |
| CHEMBL119592 | — | — | 1 | 5.51 |
| CHEMBL471122 | — | — | 1 | 5.50 |
| CHEMBL471988 | — | — | 1 | 5.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL519575 | — | EC50 | = | 1830.0 | nM | 5.74 |
| CHEMBL471297 | — | EC50 | = | 2520.0 | nM | 5.60 |
| CHEMBL471123 | — | EC50 | = | 2550.0 | nM | 5.59 |
| CHEMBL119592 | — | EC50 | = | 3080.0 | nM | 5.51 |
| CHEMBL471122 | — | EC50 | = | 3170.0 | nM | 5.50 |
| CHEMBL471988 | — | EC50 | = | 3270.0 | nM | 5.49 |