Assay Detail
Functional
CHEMBL964511
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Cytotoxicity against human DBTRG-O5MG cells assessed as cell death after 18 hrs
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Exploring the substituent effects on a novel series of C1'-dimethyl-aryl Delta8-tetrahydrocannabinol analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.51 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL119592 | — | — | 1 | 5.64 |
| CHEMBL519575 | — | — | 1 | 5.57 |
| CHEMBL471297 | — | — | 1 | 5.52 |
| CHEMBL471123 | — | — | 1 | 5.51 |
| CHEMBL471122 | — | — | 1 | 5.45 |
| CHEMBL471988 | — | — | 1 | 5.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL119592 | — | EC50 | = | 2270.0 | nM | 5.64 |
| CHEMBL519575 | — | EC50 | = | 2670.0 | nM | 5.57 |
| CHEMBL471297 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL471123 | — | EC50 | = | 3080.0 | nM | 5.51 |
| CHEMBL471122 | — | EC50 | = | 3580.0 | nM | 5.45 |
| CHEMBL471988 | — | EC50 | = | 4610.0 | nM | 5.34 |