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Assay Detail

CHEMBL964572

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of BuchE
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Cholinesterase (CHEMBL1914)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.
Pan L, Tan JH, Hou JQ, Huang SL, Gu LQ, Huang ZS.
Bioorg Med Chem Lett (2008) 18 : 3790 -3793
PubMed 18524585 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.60 4.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL456881 DEOXYVASICINONE 1 4.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL456881 DEOXYVASICINONE IC50 = 25100.0 nM 4.60