Assay Detail
Binding
CHEMBL964692
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortical membrane
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Carbon-11 labeled indolylpropylamine analog as a new potential PET agent for imaging of the serotonin transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.53 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL503609 | — | — | 1 | 7.30 |
| CHEMBL482903 | — | — | 1 | 7.27 |
| CHEMBL520301 | — | — | 1 | 6.79 |
| CHEMBL520970 | — | — | 1 | 6.16 |
| CHEMBL519819 | — | — | 1 | 5.95 |
| CHEMBL483316 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL503609 | — | Ki | = | 50.0 | nM | 7.30 |
| CHEMBL482903 | — | Ki | = | 54.0 | nM | 7.27 |
| CHEMBL520301 | — | Ki | = | 164.0 | nM | 6.79 |
| CHEMBL520970 | — | Ki | = | 685.0 | nM | 6.16 |
| CHEMBL519819 | — | Ki | = | 1120.0 | nM | 5.95 |
| CHEMBL483316 | — | Ki | = | 1990.0 | nM | 5.70 |