Assay Detail
Functional
CHEMBL966038
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Inhibition of acetylcholine-induced contraction in guinea pig ileum preincubated for 20 mins before acetylcholine challenge
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
In vitro study of the anticholinergic and antihistaminic activities of protopine and some derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.14 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL486179 | PROTOPINE | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL486179 | PROTOPINE | Kd | = | 724.44 | nM | 6.14 |