Assay Detail
Binding
CHEMBL966142
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Citrobacter freundii PER2 beta lactamase
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Citrobacter freundii |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Biochemical characterization of PER-2 and genetic environment of blaPER-2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.62 | 7.22 |
| IC50 | 2 | 7.10 | 7.17 |
Compounds Tested
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL148 | IMIPENEM ANHYDROUS | Ki | = | 60.0 | nM | 7.22 |
| CHEMBL9306 | LITHIUM CLAVULANATE | IC50 | = | 68.0 | nM | 7.17 |
| CHEMBL404 | TAZOBACTAM | IC50 | = | 96.0 | nM | 7.02 |
| CHEMBL996 | CEFOXITIN | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL702 | PIPERACILLIN | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL158 | AZTREONAM | Ki | = | 2000.0 | nM | 5.70 |