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Assay Detail

CHEMBL967317

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Functional
Inhibition of spontaneous contraction in guinea pig ileum
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cavia porcellus
Tissue Ileum
Confidence 1 — Organism
Curated By Autocuration

Target

Ileum (CHEMBL613680)
Type TISSUE
Organism Cavia porcellus

Publication

Qualitative and quantitative analysis of the active components of the essential oil from Brickellia veronicaefolia by nuclear magnetic resonance spectroscopy.
Rivero-Cruz B, Rivero-Cruz I, Rodríguez JM, Cerda-García-Rojas CM, Mata R.
J Nat Prod (2006) 69 : 1172 -1176
PubMed 16933870 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 5.83 5.83

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL491794 1 5.83
CHEMBL88244 BETA-EUDESMOL 1 5.83
CHEMBL509566 BICYCLOGERMACRENE 1 5.83
CHEMBL105432 GERMACRENE D 1 5.83
CHEMBL445740 BETA-CARYOPHYLLENE 1.0 1 5.83
CHEMBL495665 CHAMAZULENE 1 5.83
CHEMBL495645 1 5.83

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL491794 IC50 = 1490.0 nM 5.83
CHEMBL88244 BETA-EUDESMOL IC50 = 1490.0 nM 5.83
CHEMBL509566 BICYCLOGERMACRENE IC50 = 1490.0 nM 5.83
CHEMBL105432 GERMACRENE D IC50 = 1490.0 nM 5.83
CHEMBL445740 BETA-CARYOPHYLLENE IC50 = 1490.0 nM 5.83
CHEMBL495665 CHAMAZULENE IC50 = 1490.0 nM 5.83
CHEMBL495645 IC50 = 1490.0 nM 5.83