Assay Detail
Binding
CHEMBL967597
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant cyclooxygenase 2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chemical and biological investigation of N-hydroxy-valdecoxib: An active metabolite of valdecoxib.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.68 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL254418 | — | — | 1 | 7.40 |
| CHEMBL865 | VALDECOXIB | 4.0 | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL254418 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL865 | VALDECOXIB | IC50 | = | 1100.0 | nM | 5.96 |