Assay Detail
Binding
CHEMBL967622
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Inhibition of human carbonic anhydrase 1 by stopped flow technique
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.84 | 7.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL214745 | — | — | 1 | 7.07 |
| CHEMBL386049 | — | — | 1 | 6.56 |
| CHEMBL468346 | — | — | 1 | 5.62 |
| CHEMBL353498 | — | — | 1 | 5.37 |
| CHEMBL418037 | — | — | 1 | 5.36 |
| CHEMBL505415 | — | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL214745 | — | Ki | = | 85.0 | nM | 7.07 |
| CHEMBL386049 | — | Ki | = | 276.0 | nM | 6.56 |
| CHEMBL468346 | — | Ki | = | 2400.0 | nM | 5.62 |
| CHEMBL353498 | — | Ki | = | 4265.0 | nM | 5.37 |
| CHEMBL418037 | — | Ki | = | 4350.0 | nM | 5.36 |
| CHEMBL505415 | — | Ki | = | 8700.0 | nM | 5.06 |