Assay Detail
Functional
CHEMBL968335
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Cytotoxicity against drug-resistant human KB31 cells after 72 hrs by MTS reduction assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB 3-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic activity of some phenanthroindolizidine N-oxide alkaloids from Cynanchum vincetoxicum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.35 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL479473 | — | — | 1 | 7.00 |
| CHEMBL517988 | — | — | 1 | 6.96 |
| CHEMBL176049 | RHODAMINE123 | — | 1 | 5.85 |
| CHEMBL516914 | — | — | 1 | 5.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL479473 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL517988 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL176049 | RHODAMINE123 | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL516914 | — | IC50 | = | 2550.0 | nM | 5.59 |