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Assay Detail

CHEMBL968429

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as inhibition of DOPC liposomes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 1 — Organism
Curated By Autocuration

Publication

Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors.
Alexiou P, Nicolaou I, Stefek M, Kristl A, Demopoulos VJ.
Bioorg Med Chem (2008) 16 : 3926 -3932
PubMed 18267362 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.03 4.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL153 TROLOX 1 4.03
CHEMBL458568 1 4.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL153 TROLOX IC50 = 93500.0 nM 4.03
CHEMBL458568 IC50 = 95900.0 nM 4.02