Assay Detail
Functional
CHEMBL968832
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Decrease in amplitude of populations spikes in Sprague-Dawley rat hippocampal CA1 region
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Hippocampus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and structure-activity relationship studies of theophylline analogs on population responses in the rat hippocampus in vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| EC50 | 1 | 7.22 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL508710 | — | — | 2 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL508710 | — | EC50 | = | 60.0 | nM | 7.22 |
| CHEMBL508710 | — | Activity | - | — | - |