Assay Detail
Functional
CHEMBL969144
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Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth dilution assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterococcus faecalis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antibiotic bisanthraquinones produced by a streptomycete isolated from a cyanobacterium associated with Ecteinascidia turbinata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.31 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL501116 | — | — | 1 | 5.70 |
| CHEMBL508930 | — | — | 1 | 4.92 |
| CHEMBL1440 | TETRACYCLINE | 4.0 | 1 | - |
| CHEMBL500100 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL501116 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL508930 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL1440 | TETRACYCLINE | IC50 | = | 0.7 | ug.mL-1 | - |
| CHEMBL500100 | — | IC50 | = | 130000.0 | nM | - |