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Target Snapshot

CHEMBL362 Target Snapshot

Enterococcus faecalis · ORGANISM · Enterococcus faecalis

19,439Compounds
3,726Assays
2Approved Drugs
218.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Enterococcus faecalis as ChEMBL target CHEMBL362. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Enterococcus faecalis
ORGANISM · Enterococcus faecalis
As of 2026-09-13
ChEMBL target ID
CHEMBL362
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Enterococcus faecalis still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelEnterococcus faecalis
UniProt AccessionN/A

Enterococcus faecalis

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Enterococcus faecalis.

Review nameEnterococcus faecalis
OrganismEnterococcus faecalis
Clinical Profile

Clinical Phase Distribution

2
Approved
Assay Mix

Activity Type Distribution

IC50218.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5176174 6.3 IC50 500.0 Preclinical
CHEMBL4436622 6.0 IC50 1000.0 Preclinical
CHEMBL5315124 6.0 IC50 1000.0 Approved
CHEMBL4463460 5.8 IC50 1600.0 Preclinical
CHEMBL501116 5.7 IC50 2000.0 Preclinical
CHEMBL279571 5.6 IC50 2500.0 Preclinical
CHEMBL262777 5.58 IC50 2600.0 Approved
CHEMBL3585711 5.57 IC50 2720.0 Preclinical
CHEMBL5180164 5.57 IC50 2700.0 Preclinical
CHEMBL5204687 5.52 IC50 3000.0 Preclinical
Distribution

pChEMBL Value Distribution

16
5.0
10
5.5
5
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

LEVOFLOXACIN
CHEMBL5315124
Approved 1996
Assay Landscape

Assay Landscape

3,729
Total Assays
40
Tested Compounds
3
Assay Types
Functional — 3,705 assays, 40 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 3,560 38 5.1
assay format 145 2 4.8
ADME — 18 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 18 0
Binding — 6 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 6 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine