Assay Detail
Binding
CHEMBL969396
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Inhibition of wild type p38alpha
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Chemical genetics define the roles of p38alpha and p38beta in acute and chronic inflammation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 10.05 | 10.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL199679 | — | — | 1 | 10.10 |
| CHEMBL303144 | — | — | 1 | 10.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL199679 | — | IC50 | = | 0.08 | nM | 10.10 |
| CHEMBL303144 | — | IC50 | = | 0.1 | nM | 10.00 |