Assay Detail
Binding
CHEMBL969397
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of p38alpha T106M mutant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chemical genetics define the roles of p38alpha and p38beta in acute and chronic inflammation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.51 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL199679 | — | — | 1 | 7.55 |
| CHEMBL303144 | — | — | 1 | 7.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL199679 | — | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL303144 | — | IC50 | = | 34.0 | nM | 7.47 |