Assay Detail

CHEMBL969755

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Functional

Antiproliferative activity against mouse +SA cells assessed as cell viability after 4 days by MTT assay

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

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NON-PROTEIN TARGET (CHEMBL3879801) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Mus musculus
Cell Type	+SA cell
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Sinulodurins A and B, antiproliferative and anti-invasive diterpenes from the soft coral Sinularia dura.

Radwan MM, Manly SP, El Sayed KA, Wali VB, Sylvester PW, Awate B, Shah G, Ross SA.
J Nat Prod (2008) 71 : 1468 -1471
PubMed 18630962 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.16	5.16

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL121305	DELTA-TOCOTRIENOL	—	1	5.16

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL121305	DELTA-TOCOTRIENOL	IC50	=	7000.0	nM	5.16