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Assay Detail

CHEMBL970019

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat recombinant DNA polymerase beta after 60 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

DNA polymerase beta (CHEMBL4343)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

A new 7,8-euphadien-type triterpenoid from Brackenridgea nitida and Bleasdalea bleasdalei that inhibits DNA polymerase beta.
Deng JZ, Starck SR, Sun DA, Sabat M, Hecht SM.
J Nat Prod (2000) 63 : 1356 -1360
PubMed 11076551 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.01 5.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL519411 1 5.01

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL519411 IC50 = 9700.0 nM 5.01