Assay Detail
Binding
CHEMBL970725
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to guinea pig kappa opioid receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-antitussive activity relationships of naltrindole derivatives. Identification of novel and potent antitussive agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.47 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL567175 | NALTRINDOLE | — | 1 | 7.52 |
| CHEMBL514693 | — | — | 1 | 5.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL567175 | NALTRINDOLE | Ki | = | 30.4 | nM | 7.52 |
| CHEMBL514693 | — | Ki | = | 3911.0 | nM | 5.41 |