Assay Detail
Functional
CHEMBL971058
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Cytotoxicity against human HL60 cells after 96 hrs by MTT assay
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic lavandulyl flavanones from Sophora flavescens.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.86 | 4.95 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL453642 | LEACHIANONE A | — | 1 | 4.95 |
| CHEMBL243148 | SOPHORAFLAVANONE G | — | 1 | 4.90 |
| CHEMBL496451 | — | — | 1 | 4.86 |
| CHEMBL243796 | KURARINONE | — | 1 | 4.73 |
| CHEMBL242341 | FORMONONETIN | 2.0 | 1 | - |
| CHEMBL334918 | MAACKIAIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL453642 | LEACHIANONE A | IC50 | = | 11300.0 | nM | 4.95 |
| CHEMBL243148 | SOPHORAFLAVANONE G | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL496451 | — | IC50 | = | 13700.0 | nM | 4.86 |
| CHEMBL243796 | KURARINONE | IC50 | = | 18500.0 | nM | 4.73 |
| CHEMBL242341 | FORMONONETIN | Activity | - | — | - | |
| CHEMBL334918 | MAACKIAIN | Activity | - | — | - |