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Assay Detail

CHEMBL971470

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to EP1 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Prostaglandin E2 receptor EP1 subtype (CHEMBL1811)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of potent and selective DP1 receptor antagonists in the azaindole series.
Leblanc Y, Roy P, Dufresne C, Lachance N, Wang Z, O'Neill G, Greig G, Denis D, Mathieu MC, Slipetz D, Sawyer N, Tsou N.
Bioorg Med Chem Lett (2009) 19 : 2125 -2128
PubMed 19307115 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 4.54 4.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL484778 1 4.54
CHEMBL483991 1 4.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL484778 Ki = 28500.0 nM 4.54
CHEMBL483991 Ki = 28500.0 nM 4.54