Assay Detail
Functional
CHEMBL972082
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Cytotoxicity against human GTB cells after 5 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | GTB |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic activities of hypocretenolides from Leontodon hispidus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.77 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL503318 | — | — | 1 | 7.16 |
| CHEMBL365306 | — | — | 1 | 6.58 |
| CHEMBL338474 | HELENALIN | — | 1 | 6.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL503318 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL365306 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL338474 | HELENALIN | IC50 | = | 270.0 | nM | 6.57 |