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Assay Detail

CHEMBL972435

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Functional
Antitumor activity against human medulloblastoma cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Medulloblastoma cell
Confidence 1 — Organism
Curated By Autocuration

Publication

Hedgehog-Gli signaling pathway inhibitors as anticancer agents.
Mahindroo N, Punchihewa C, Fujii N.
J Med Chem (2009) 52 : 3829 -3845
PubMed 19309080 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL472997 1 5.00
CHEMBL516246 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL472997 IC50 = 10000.0 nM 5.00
CHEMBL516246 IC50 = 10000.0 nM 5.00