Assay Detail
Binding
CHEMBL972724
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ribosomal activity in erythromycin-resistant Propionibacterium acnes P95 with G2057A mutation in domain V of 23S rRNA assessed as luciferase production by transcriptional and translational assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cutibacterium acnes |
| Subcellular | Ribosome |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Activity of the novel macrolide BAL19403 against ribosomes from erythromycin-resistant Propionibacterium acnes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.29 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405863 | — | — | 1 | 6.92 |
| CHEMBL532 | ERYTHROMYCIN | 4.0 | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405863 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL532 | ERYTHROMYCIN | IC50 | = | 2200.0 | nM | 5.66 |