Assay Detail
Binding
CHEMBL972814
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of LPS-induced COX2 activity in C57BL/6J mouse peritoneal macrophages by RIA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Triterpene saponins from clematis mandshurica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.82 | 9.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL118 | CELECOXIB | 4.0 | 1 | 9.29 |
| CHEMBL525269 | CLEMATOMANDSHURICA SAPONIN B | — | 1 | 5.59 |
| CHEMBL526701 | CLEMATOMANDSHURICA SAPONIN A | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL118 | CELECOXIB | IC50 | = | 0.51 | nM | 9.29 |
| CHEMBL525269 | CLEMATOMANDSHURICA SAPONIN B | IC50 | = | 2580.0 | nM | 5.59 |
| CHEMBL526701 | CLEMATOMANDSHURICA SAPONIN A | IC50 | = | 2660.0 | nM | 5.58 |