Assay Detail
Binding
CHEMBL973091
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Inhibition of FGFR1 by cellular assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.39 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL189584 | PD-173074 | — | 1 | 7.68 |
| CHEMBL459850 | — | — | 1 | 7.10 |
| CHEMBL509032 | TAE-684 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL189584 | PD-173074 | EC50 | = | 21.0 | nM | 7.68 |
| CHEMBL459850 | — | EC50 | = | 80.0 | nM | 7.10 |
| CHEMBL509032 | TAE-684 | EC50 | > | 1000.0 | nM | - |