Assay Detail
Binding
CHEMBL973337
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Inhibition of flag-tagged HDAC4 by Biomol assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.63 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL356066 | DACINOSTAT | 2.0 | 1 | 9.00 |
| CHEMBL430060 | APICIDIN | — | 1 | 8.92 |
| CHEMBL1791402 | — | — | 1 | 7.06 |
| CHEMBL27759 | ENTINOSTAT | 3.0 | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL356066 | DACINOSTAT | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL430060 | APICIDIN | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL1791402 | — | IC50 | = | 88.0 | nM | 7.06 |
| CHEMBL27759 | ENTINOSTAT | IC50 | = | 3017.0 | nM | 5.52 |